Struggling to find the right participants for your clinical trials?

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PreMatch 360 is a pre-screening solution that overcomes your toughest recruitment challenges. We harness the innovations pioneered by the Duke Clinical Research Institute (DCRI) and the i-Cubed Center to minimize screen failure, increase engagement, and accelerate trial timelines.

The PreMatch 360 Difference

With PreMatch 360, you match with pre-screened participants ready to enroll in your trial, ensuring a smoother, faster, and more successful process from the start.

Deep Data Matching

We combine multi-domain data—self-reported data, imaging, biological samples, EHR, and social determinants of health—to give you a complete picture of each potential participant’s eligibility, engagement level, and likelihood to enroll and complete the trial.

Expanded Reach with Hybrid Recruiting

We integrate site-based and direct-to-patient recruitment strategies, reaching a broader, more diverse pool of potential participants and breaking free from traditional recruitment constraints.

Trusted Community Engagement

We tap into Duke’s extensive network and engage directly with communities to ensure your trials include representative populations.

Seamless Central Coordination

From early recruiting to trial completion, we provide centralized coordination between sites, study teams, and participants, smoothing communication gaps and reducing administrative burden.

See the real-world impact of PreMatch 360

Explore Case Studies

PreMatch 360 is the engine powering
faster and more reliable recruiting.

We work closely with the study team and community to customize our approach and strategy. No two studies are exactly the same.
The DCRI network gives us unique access to site-based, community, and direct-to-patient channels. We select the combination of recruiting methods best suited for your patient population.
Qualified leads are not just a list of email addresses from a database. These are real patients who've already expressed interest in participating in your area of research.
We deploy a combination of pre-screening techniques, ranging from surveys to medical interviews to imaging and labs.
Your final pre-screened cohort is highly targeted, engaged, and far more likely to pass your screening protocol than other patients.
We provide centralized coordination between sites, study teams, and participants.
The ultimate goal: providing you great participants—faster, more reliably, and with less effort for your sites and your study team.

Scoping Phase

We work closely with each study team and community to customize our approach.

Recruit

The DCRI network gives us unparalleled access to site-based, community engagement, and direct-to-patient channels. Depending on the needs of the study, we can use any combination of the following recruiting tools:

  • Community Partners
  • Providers
  • Public Data
  • Digital Ads
  • EHR Data
  • Claims Data

The result is a list of qualified leads.

Pre-Screen

PreMatch360 is the only solution that integrates data science and multi-domain screening data. Depending on the needs of the study, we can use any combination of the following tools to pre-screen the list of qualified leads:

  • Surveys
  • Medical Interviews
  • SDOH Data
  • At-Home Biomarkers
  • Labs, Simple Imaging
  • EHR Data

The result is a pre-screened cohort.

Engage

From early recruiting to trial completion, we provide centralized coordination between sites, study teams, and participants. The result is enrolled and engaged participants who are less likely to dropout.

Compare PreMatch 360

PreMatch 360 offers significant benefits over traditional recruiting methods.

Feature PreMatch 360 Direct-to-Patient Advertising Site Recruiting
Access to larger patient populations
No
Lower burden on site staff
No
Reduced sample bias
No
No
Lower screen-fail rates
No
Lower dropout rates
No
Accelerated trial timelines
No
No

Powered by Duke Clinical Research Institute

A male doctor explains the situation to a female patient in a comfortable room

PreMatch 360 comes from a dedicated team of clinicians and researchers at Duke Clinical Research Institute and product innovators at the i-Cubed Center. Leveraging a suite of Duke innovations in clinical research and data science, we’ve developed a pre-screening solution that unlocks modern clinical trial recruitment for every organization. PreMatch 360 is powered by our team’s unique combination of clinical expertise, relentless focus on patient needs, and cutting-edge technology. We’re passionate about accelerating medical breakthroughs, and we’re excited to partner with you on that journey.

A male doctor explains the situation to a female patient in a comfortable room

Ready for smoother, faster, more successful trials?

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