Optimizing recruitment with research-ready cohorts

PreMatch360 is a pre-screening solution that overcomes your toughest recruitment challenges. We harness the innovations pioneered by the Duke Clinical Research Institute (DCRI) and the i-Cubed Center to minimize screen failure, increase engagement, and accelerate trial timelines.

Recruitment is a Bottleneck

80%

Clinical trials that fail to meet their enrollment timelines

50%

Trial sites that under-enroll

>50%

Screen failure rates in some therapeutic areas

$800K

Cost wasted on each day of study delays

Research-ready cohorts remove uncertainty from enrollment.

Traditional Funnel

Large top, massive screen failure/dropout, only a trickle randomizes.

PreMatch360 Funnel

Smaller top, higher quality, most flow through to randomization.

The PreMatch360 Difference

With PreMatch 360, you match with pre-screened participants ready to enroll in your trial, ensuring a smoother, faster, and more successful process from the start.

Deep Profile Matching

Integrates data science and multi-domain data  (EHR, claims, self-reported, imaging, biological samples, SDOH, etc.)

Hybrid Recruitment Sources

Unparalleled access to site-based, community engagement, and direct-to-patient recruitment

Seamless Coordination

Centralized coordination between sites, study teams, and participants

Evidence-Based Recruitment Strategy

Our experts in patient recruitment help turn multi-domain data into actionable recruitment strategies

Extensive Clinical Expertise

Our team of clinical experts ensures every decision is grounded in proven trial experience

Established Network of Community Partners & Sites

Our network of community anchors and research sites allows trusted local relationships to drive cohort development

PreMatch360 is the engine powering
faster and more reliable recruiting.

We work closely with the study team and community to customize our approach and strategy. No two studies are exactly the same.
The DCRI network gives us unique access to site-based, community, and direct-to-patient channels. We select the combination of recruiting methods best suited for your patient population.
Qualified leads are not just a list of email addresses from a database. These are real patients who've already expressed interest in participating in your area of research.
We deploy a combination of pre-screening techniques, ranging from surveys to medical interviews to imaging and labs.
Your final pre-screened cohort is highly targeted, engaged, and far more likely to pass your screening protocol than other patients.
We provide centralized coordination between sites, study teams, and participants.
The ultimate goal: providing you great participants—faster, more reliably, and with less effort for your sites and your study team.

Scoping Phase

We work closely with each study team and community to customize our approach.

Recruit

The DCRI network gives us unparalleled access to site-based, community engagement, and direct-to-patient channels. Depending on the needs of the study, we can use any combination of the following recruiting tools:

  • Community Partners
  • Providers
  • Public Data
  • Digital Ads
  • EHR Data
  • Claims Data

The result is a list of qualified leads.

Pre-Screen

PreMatch360 is the only solution that integrates data science and multi-domain screening data. Depending on the needs of the study, we can use any combination of the following tools to pre-screen the list of qualified leads:

  • Surveys
  • Medical Interviews
  • SDOH Data
  • At-Home Biomarkers
  • Labs, Simple Imaging
  • EHR Data

The result is a pre-screened cohort.

Engage

From early recruiting to trial completion, we provide centralized coordination between sites, study teams, and participants. The result is enrolled and engaged participants who are less likely to dropout.

Tangible Impacts

Faster time to FPI/LPI

Lower screen failures and improved retention

Study design insights in real time

Proven across diverse populations

More predictable study investment

Centralized coordination leads to less site burden

Explore Case Studies
two hands in blue latex gloves fill a syringe with a vaccine

Compare PreMatch360

PreMatch360 offers significant benefits over traditional recruiting methods.

Feature PreMatch360 Direct-to-Patient Advertising Site Recruiting
Access to larger patient populations
No
Lower burden on site staff
No
Reduced sample bias
No
No
Lower screen-fail rates
No
Lower dropout rates
No
Accelerated trial timelines
No
No

Powered by Duke Clinical Research Institute

PreMatch360 comes from a dedicated team of clinicians and researchers at Duke Clinical Research Institute and product innovators at the i-Cubed Center. Leveraging a suite of Duke innovations in clinical research and data science, we’ve developed a pre-screening solution that unlocks modern clinical trial recruitment for every organization.

PreMatch360 is driven by our team’s unique combination of clinical expertise, relentless focus on patient needs, and cutting-edge technology. We’re passionate about accelerating medical breakthroughs, and we’re excited to partner with you on that journey.

2,500+

Phase II-IV trials & outcomes research projects completed

3,675+

FDA Submissions since 2008

2MM+

Patients enrolled

10K+

Studies published

Let’s build your next cohort together!

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