Case Study: More Than Headache Relief: What Kids Told Us About Migraine Treatment
The Challenge
Following a successful new adult migraine therapy, a pharmaceutical
company wanted to launch a series of pediatric trials. But traditional
recruitment methods were seeing extremely high screen failure rates and
slow enrollment.
The PreMatch360 Solution
The DCRI team created a cohort of clinically phenotyped children with migraine, ready for trial activation. We leveraged our network of community partners to engage with families and patients across multiple touchpoints. Patient preferences helped us shape a participant-friendly protocol.Why It Matters
PreMatch360 quickly delivered eligible, engaged participants and facilitating downstream trial performance.
Impact
Pre-screened cohort delivered to 10 academic and community-based research sites.
200 trial-ready participants enrolled
3 peer-reviewed publications (1, 2, 3)
Patient insights that shaped protocol design and retention strategies
Headache. 2020 Feb;60(2):405-415. Pediatr Neurol. 2023 Sep:146:79-84.