Case Study: Overcoming MPOX: Building Vaccine-Ready Cohorts in the Face of Stigma
The Challenge
During the MPOX outbreak, stigma severely limited vaccine uptake and healthcare engagement, particularly in marginalized communities. Public health efforts were hindered by a lack of data on the real barriers preventing access.
The PreMatch360 Solution
PreMatch360 rapidly developed a responsive, cross-sectional cohort drawn from communities most affected by stigma and exclusion. Through targeted outreach and culturally sensitive engagement, we:
- Deployed surveys to assess stigma, trust, and access barriers
- Quantified how social factors shaped healthcare-seeking behavior
- Identified population-specific concerns around testing, treatment, and vaccination
- Delivered insights to inform vaccine and public health strategy
Why It Matters
PreMatch360 went beyond identifying who was at risk. We built the
path to reach them. Sponsors and public health leaders now have a
data-backed roadmap to engage marginalized populations faster,
more effectively, and with greater trust.
Impact
Identified key barriers to MPOX vaccine access in at-risk communities
Enabled tailored outreach strategies for future interventions
Built a foundation for a vaccine-ready cohort with actionable segmentation
Informed health departments and funders on stigma-aware public health approaches
Findings submitted for peer-reviewed
publication